University of Dresden

Partner 5: TUD

Team Leader: PD Dr. Michaela Jaksch, MD (Dresden University, Germany)

Team Members:

  • Dr. Jochen Schäfer, MD (Dresden University, Germany)
  • Dr. Johannes Mayr, PhD (Childrens Hospital, Salzburg, Austria)
  • Dr. Sandra Jackson, MD (Dresden University, Germany)

Dr. Jaksch’s laboratory is an important center for molecular and biochemical analyses in mitochondrial disorders in Germany. Scientific equipment includes all standard analyzing systems: Cell culture facilities. Tandem Mass Spectroscopy. Basic molecular biology facilities: Southern Blot, Western Blot, PCR, and cloning, Real-time PCR ABI-prism 310 automated sequencer. Microscopes for immunofluorecence and basic facilities for biochemistry.

The group in Dresden is working on molecular causes of different mitochondrial disorders. The participation of this group guarantees access to patients with neurological diagnoses, which should be considered in secondary CoQ deficiency disorders. Clinical characterization of patients (Schäfer). Evaluation of HPLC testing in different tissues (Schäfer, Jackson). Respiratory chain analyses (Mayr). The scientists are experts in the field of mitochondrial disorders.

The Dresden group is coordinated by PD Dr. Michaela Jaksch at the Department of Neurology, Dresden University. Her publication list encompasses about 40 original papers. One PhD student and one experienced technician will be also participants of this project.

Contact: Sandra Jackson

Ubigenes :: Genetics of coenzyme Q deficiency in humans